I would love to say that "So Many Systems, So Little Time" - by Julia Camenisch in Videomaker's Hi-Def Guide (winter 2006) has the answers for you. Sadly, this article does little to shed light on hardware differences, editing systems, or anything else, for that matter.
Instead, "the Moving Picture - Meet the New Beast" by Jan Ozer in the January 2007 issue of Event DV, not only answers your questions, but does so relative to video editing purposes. I recommend you get that issue and read page 72.
As far as that goes, I heartily recommend Event DV to all event videographers. Other than their maddening policy of trying to limit authors to a single page, it's an excellent magazine.
In short - no you do not open multiple windows of your NLE. Hyperthreading is what programs had to be written to take advantage of, but I believe (OK, I've only scanned the article) Core 2 Duo machines make just about any program run faster. They even run faster than single core CPUs that are rated at a higher clock rate.